I've been fortunate enough to not be affected by the other bugs people have been reporting with Windows 7, but lately after quite a bit of use I've been seeing wierd issues with IE 8 on two different computers with Windows 7 Ultimate RTM.
After using the same IE instance for a while, I will eventually be unable to use the forward/back buttons, and have to click the home button ~5 times to get it to work. Flash (several different versions, btw) crash individual tabs. Occasionally a large page will have IE "stop responding" for several seconds.
Anyone else experience any IE 8 wierdness? I don't remember any of these issues in the beta or RC.