More than likely, if you are picking on a certain IP address, you will want to block them completely, not just a certain port
iptables -A INPUT -s 10.10.10.0/24 -j DROP
will blocks the whole /24, just drop the /24 and add last real octet to pick on the single IP.
Make it persistent
/sbin/service iptables save
I distribute a script to put offenders in, and it also optionally blocks certain foreign IPs (don't you get tired of all the APNIC brute forces and dDOSs?) for Linux and Win.
Helped cut down my spam too.