For one thing I code my email addys so they look like &123; but render perfectly in a browser.
Secondly, I do a whois on the IP or domain that originated it, (not the addy in the return field) then send them a email berating them, and telling them to prevent their clients from sending me any more spam. If I get a autorepsonse, and the spam continues, I am now armed with all I need.
I set that box to forward all emails to the address I complained to. Their autoresponder will respond everytime a spam gets forwarded, as well as every time an autoreponse is generated, and so on. Kinda like an autogenerated mail bomb, and the good part is they did it to themselves.
After a couple of weeks, I take it off and see if it stopped. It usually does.