It sounds great...5 geographically dispersed nameservers from a large registrar. Sure beats 2 pointing to the same hosting server.
But a few times in the past week when I've tried querying the eNom nameservers (both from my PC and from a different web site), I've gotten time-out errors (no response). I figure no big deal...if one is down, one of the others will work because they're geographically dispersed. That didn't turn out to be the case.
So on paper, it's the most reliable nameservers I've used. In reality, it doesn't seem that way.
At any rate, I love how I can make DNS changes that are instantly recognized through my ISP.