I've been on WHT for a while now, and thought this subforum would be an appropriate place to show off a guide to optimizing apache that I wrote. This guide is geared specifically towards users who are looking to set up their own cgi proxy using J Marshall's CGI Proxy script, but most of the article applies for any mod_perl site in particular, or any site using apache in general.
These days it's probably better to replace Apache all together...
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with what? Apache is fully featured and works well. If you configure it properly it also gives decent performance. I suppose I could eek out more by using something with a smaller footprint, or as mentioned in the article, you could throw a squid cache in front of it so it doesn't have to load up as many processes in the first place.