The files within /home/username/.autorespond/* should have the same owner and chmod 644.
If that is correct, try checking the logs(/var/log/exim_mainlog) and see what haapens when you send the mail. If the autoresponder is working, you should see something like the following:
If its broken, you may see something like the following:
1Fhkdj-0004j8-TK** |/usr/local/cpanel/bin/autorespond [email protected] /home/username/.autorespond ([email protected]) <[email protected]> R=virtual_aliases_nostar T=virtual_address_pipe: delivery to pipe forbidden
Also check if the pipe_transport option is enabled in the exim configuration. You can also try a force exim upgrade(after taking a backup of /etc/exim.conf).
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