I don't think it would be a brilliant idea because the best ones are mostly taken, and the other ones aren't good enough.
You have to consider the fact that italians are familiar with that extension, few others from around the world are.
Also, it's not as cheap as .com ones if you want to buy a few.
And there are quite a few limitations (ie: just one per private person) and some burocracy ( I had to send a fax 8 times before they would accept my ridiculously useless liability declaration and that's because they could not read my signature properly and they weren't telling me!Only after the 6th fax they informed me why they weren't accepting my application!)
Italians are usually after .coms rather than .its and that of course is also because in italy you don't say "it".
That's my opinion.