There are plenty of templates to monitor various applications and check for a specific response - and usually, this will involve communications over a specific port - so yes, there might be something that covers what you are trying to do if we had more info to understand what it is you are doing..
CPanel Shared and Reseller Hosting, OpenVZ VPS Hosting. West Coast (LA) Servers and Nodes
Running Linux since 1.0.8 Kernel!
Providing Internet Services since 1995 and Hosting Since 2004