In terms of location, iWeb's servers are in the Montreal area, which is actually a pretty decent location for the East Coast U.S. as well. I've seen amazing Host-Tracker.com round the world scores for the sites they host, though.
I suppose, since you're investing a bundle on dedicated, you might want to check their sites with a round-the-world tracking service and see what sort of performance you can get if you intend to have a global presence.
Host/Executive Producer, The Paracast, www.theparacast.com
I do not represent the hosting industry!