any advice would be appreciated..
For a seperate venture i'm active in, I'm looking for a simple shopping cart that allows one to buy domains and nothing else. It should have an API with enom and ideally have a couple payment processors to choose from. Most of the carts i've seen seem to require you to work in conjunction with web hosting panels without really stripping down to just selling domains with reoccuring life.

Sounds to me like the answer to your needs is AWBS. http://awbs.com

They work with enom and have multiple payment modules that can be used. You can order just the domain edition that will do everything you need as far as domain management is concerned.

The domain only edition is $110.00 as opposed to $169.00 for the full edition.