How do I have a photoshop layout,

put a iFrame in one of the table data cells and not mess up the site? Because it keeps messing up :(
even when I put

<td background="imagename.jpg">
<iframe>

I would suggest that you slice the image in photoshop export the .jpg files then open them in dreamweaver and insert a iframe there.

<iframe src="blah.blah" target="iframe.html">

make sure all links are set to open in the target'"iframe.html"

I should be able to do it without dreamweaver. I did it before but I forget how I did it.