I keep on getting my box flooded by enzine web tools newsletter(yea newsletter alright, they send out 10 a day), its not even a newsletter to begin with, they just send junk promoting web sites... I never signed up to begin with. I clicked on the link at the bottom of the email, removed my name from the list about 20 times. I am still getting this spam. Its pissing me off, how can i get rid of these aholes once and for all?

wellll probably by clicking to remove yourself.....you just confirmed your email for them!
Check out spamcop.net
and report the spam.

Yeah, unfortunately 'removing yourself' often really says to them, "Send this guy tons more crap!" which isn't what you want. I try to filter out the emails (tip: anything that says, "this isn't spam" ... is spam generally), so if you can find key words or phrases in the emails, you can set your email client to automatically file them in the virtual circular file (trash)