Anyone know of an accouting system that specifically supports accounting from an Affiliates/Referrals standpoint... one which keeps track and calculates sales generated from affiliates and applicable commissions on each sale and cumlatively.

I don't know if it's an all-in-one package like you're seeking, but I know they have an affiliate tracking program at

Mal's E-Commerce:
http://www.mals-e.com

:D HTH... Bailey