MiniPortal is a suite of servers for hosting one or more websites on your own Windows PC. No monthly fees.

Software includes:
Web server
FTP server
Perl
MiniPortal Administrator (web 'Control Panel')
MiniPortal Manager (WinGUI)

Free plugins:
PHP
MySQL
Discussion boards (Phorum, PhpBB, YaBB)
Webmail (requires ISMail -- see below)

Versions:
MiniPortal SOHO: host 1 domain, $49 USD
MiniPortal: host unlimited domains, $99 USD

Also available is ISMail, a Windows mail server with SMTP, POP3, IMAP4, Webmail, and unlimited domains and accounts for $99 USD.

Free 30-day trial downloads:
InstantServers, Inc.
http://instantservers.com
webmaster@instantservers.com